On Earth, the cardinal directions are straightforward. The arrow on a compass points to the nearest magnetic pole. You can then use it to travel anywhere on Earth.
In space, the idea of anything being “central” enough to be used as a “North” (since the universe has no center) or being fixated enough to not somehow pose issues is more convoluted.
If you were a pioneer of space exploration, what would your “North” be?
This.
If you’re wondering why, this is the centre of our Galaxy. Of course if you’re planning on intergalactic travel, you might have some issues, but before you get too worried about it, exploring the current galaxy is going to take a while.
Wikipedia
Edit: The link to the super massive black hole at the centre of our galaxy wasn’t working.
The link worked for me
Yeah, in the unedited version of my reply, the asterisk wasn’t detected as part of the URL which lands you at Sag A, not Sag A*.
SagA* is as good as any other galactic center for intergalactic north too. There’s really no reason to pick a different one.