Summary

The FDA has proposed phasing out oral phenylephrine, a common decongestant in cold medicines like Sudafed PE and DayQuil, after studies showed it is no more effective than a placebo.

The drug, ineffective when swallowed due to breakdown in the stomach, remains usable in nasal sprays.

Alternatives include pseudoephedrine, nasal sprays, and steroid treatments like Flonase.

The regulatory process to remove phenylephrine could take over a year, but experts argue removing ineffective options will help consumers choose better remedies for congestion. Drugmakers are expected to challenge the proposal.

  • watson387@sopuli.xyz
    link
    fedilink
    English
    arrow-up
    81
    arrow-down
    1
    ·
    edit-2
    3 days ago

    Pseudoephedrine. In the US, you have to go to the pharmacy counter and ask for it, but it works.

    • CrayonRosary@lemmy.world
      link
      fedilink
      English
      arrow-up
      22
      ·
      3 days ago

      And it works great! I woke up with a ton of sinus pain yesterday. My whole face ached. Two pseudoephedrine and it was gone in an hour.

    • AllNewTypeFace@leminal.space
      link
      fedilink
      English
      arrow-up
      12
      arrow-down
      41
      ·
      3 days ago

      The problem is that it is legally an evil drug because you can make meth from it, so it remains heavily restricted. There are more effective ways to make meth at commercial scale than by buying and crushing up cold and flu tablets, but it’s a question of moral principle, i.e. not condoning evil.

      • ITeeTechMonkey@lemmy.world
        link
        fedilink
        English
        arrow-up
        48
        arrow-down
        3
        ·
        3 days ago

        This is some dumb pearl clutching bullshit.

        With this asinine logic, buying apples are condoning evil because their seeds contain cyanide and though there are more effective ways to create cyanide at commercial scale than buying apples and extracting the small amount of cyanide from the seeds it’s still a question of moral principle i.e not condoning evil.

        • Psythik@lemmy.world
          link
          fedilink
          English
          arrow-up
          4
          ·
          2 days ago

          What’s even bigger bullshit is that you can simply buy Benzedrine from the nasal decongestant aisle instead, remove the cotton wick and soak it in an acid (like lemon juice), and in 24 hours you have the same kind of meth they gave the Nazis. For four dollars. It’s literally just sitting there on the shelf for anyone to buy.

          Everything in life is made up and none of the points matter.

        • shalafi@lemmy.world
          link
          fedilink
          English
          arrow-up
          14
          arrow-down
          5
          ·
          3 days ago

          Yeah, but people are actually making meth from pseudoephedrine and no one is making cyanide from apples.

          And yes, I hate having to go inside to buy it as I use it nearly every day.

      • chiliedogg@lemmy.world
        link
        fedilink
        English
        arrow-up
        1
        ·
        2 days ago

        It’s not that hard. The only real issue is when the pharmacy is closed and you’re trying to buy one a holiday or after-hours. I just keep some spare pseudoephedrine in the medicine cabinet to hold me over until the pharmacy opens.

      • Hugin@lemmy.world
        link
        fedilink
        English
        arrow-up
        5
        arrow-down
        2
        ·
        3 days ago

        They spend more money and chemistry making pseudoephedrine hard to make into meth then they do on the everything else in the medicine. It’s also why meth labs tend to blow up when they didn’t with with standard pseudoephedrine.